Keep up with EV literature

Clinical-scale bioreactor production of hiPSC-derived extracellular vesicles modulates miRNA and protein cargo to enhance angiogenic function

Ana Meliciano, João Jacinto, Catarina Freitas, Marta H.G. Costa, Miguel de Almeida Fuzeta, Margarida Serra. Trends in Biotechnology, March 2026.

Bioengineered baculovirus-derived extracellular vesicles loaded with of γ-carboxylated Gla-rich protein: Dual modulation of inflammation and vascular calcification

Carla Viegas, Simon Pichard, Joana Carreira, Adélia Ova, Nathalie Troffer-Charlier, Teresa M. Maia, Evelina Edelweiss, Anjos L. Macedo, António Matos, Tiago Q. Faria, Sofia M. Calado, Carina Monico, Simon Devos, Francis Impens, Christine Schaeffer-Reiss, Sarah Cianférani, Cristina Peixoto, Arnaud Poterszman, Dina Simes. Biomaterials Advances, July 2026.

Extracellular vesicles-mediated delivery of SpCas9 RNPs for therapeutic gene editing in Spinocerebellar Ataxia Type 3

Kevin Leandro, David Rufino-Ramos, Sara M Lopes, Francisca Santos Silva, Paulo Rodrigues-Santos, Ana Carolina Silva, Ana Rita Fernandes, Carina Henriques, Dina Pereira, Diana Lobo, Guilherme L Gabriel, Rosário Faro, Rui Jorge Nobre, Pedro R L Perdigão, Benjamin P Kleinstiver, Luís Pereira de Almeida. Biomaterials, March 2026.

Bioreactor expansion of human neural progenitor cells for exosome scalable production and miRNA-engineering

Miriam Corraliza-Gomez, Marta Ianni, Diogo E. S. Nogueira, William O. S. Salvador, Mafalda Miguéis, Monica Garcia-Alloza, Carlos A. V. Rodrigues, Joaquim M. S. Cabral & Dora Brites. Journal of Biological Engineering. February 2026.

Integrative Proteomics of Extracellular Vesicles from hiPSC-Derived Cardiac Organoids Reveals Heart Tissue-like Molecular Representativity

Carlos Miguel Vital, José Manuel Inácio, Ana Sofia Carvalho, Hans Christian Beck, Rune Matthiesen, José António Belo. International Journal of Molecular Sciences, January 2026.

Cyanobacterial Extracellular Vesicles as Protein Carriers: Towards Fish Vaccination

Jorge Matinha-Cardoso, Gabriela Gonçalves, Filipe Coutinho, Steeve Lima, Lourenço Bonneville, Mónica Serrano, Paula Tamagnini, Aires Oliva-Teles, Ana Couto, Cláudia R. Serra, Paulo Oliveira . Microbial Biotechnology, January 2026.

Retinal pigment epithelium-derived extracellular vesicles mediate outer blood retinal barrier disruption in response to AMD-related stress

Beatriz Martins, Raquel Boia, Diana Correia, Teresa Ribeiro-Rodrigues, José Ramalho, António Francisco Ambrósio, Henrique Girão & Rosa Fernandes. Cell Communication and Signaling, December 2025.

Systematic review of changes in extracellular vesicles associated with obstructive sleep apnoea: implications for diagnosis and treatment

Bárbara Santos , Bárbara Ramalho, Angela Relógio, Cláudia Cavadas, Laetitia S. Gaspar and Ana Rita Álvaro . ERS Publications, November 2025.

Aβ Modulates Extracellular Vesicles Proteomic Profile Impacting Phosphorylation Mediators

Margarida Vaz, Tânia Soares Martins, Diogo Trigo, Odete A. B. da Cruz e Silva, Francisco Amado, Rui Vitorino & Ana Gabriela Henriques . Molecular Neurobiology, November 2025.

Seminal fluid extracellular vesicles restore human sperm osmoregulation after cystic fibrosis transmembrane conductance regulator inhibition

Sara C. Pereira, Oleksandra Fomichova, Isabel Damião, Sara Oliveira, Vasco Almeida, Mariana P. Monteiro, Mário Sousa & Raquel L. Bernardino. Scientific Reports, December 2025.

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

We’re excited to highlight the latest review co-authored by EVCA members Luís Carvalho Ferraz, Paulo Pereira, and João Vasco Ferreira. Congratulations to all authors!

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