Research Fellow: Neuronal-derived EVs in Neurodegenerative Disease - UK

Francis Crick Institute / UCL, led by Prof. Sonia Gandhi's lab (Neurodegeneration Biology Laboratory) are seeking a Research Fellow to join their lab | Working across a range of human models, including patient-derived cells, biofluids, and brain tissues, the candidate will further develop skills in molecular biology, cell imaging, and the analysis of complex datasets within a dynamic translational neuroscience research environment | The candidate will work on the isolation and analysis of neuronal-derived EVs from stored biosamples across several international studies to better understand disease mechanisms and identify biomarkers of disease progression. Established methods and protocols for EV isolation and characterisation will be used. In addition, EVs will be isolated from induced pluripotent stem cell (iPSC)-derived neuronal cultures from patients with Parkinson’s disease to investigate disease propagation in vitro | Fixed-term through Sept 2027.